Val,
If you have the waveform as a baseband I/Q file, or the ability to create a LoRa waveform with a tool like MATLAB, and the sample rate of the file doesn’t exceed 50MS/s, then yes you can use the VSG60 to transmit this waveform using the ARB output mode. Our software does not have native LoRa waveform creation capability, you would have to provide your own waveform.